Do you have ductal carcinoma in situ DCIS or breast cancer that can be removed with surgery? If so, you may be able to choose which type of breast surgery to have. Often, your choice is between breast-sparing surgery surgery that takes out the cancer and leaves most of the breast and a mastectomy surgery that removes the whole breast.
August 26,by NCI Staff. Ductal carcinoma in situ, or DCIS, is a noninvasive condition in which abnormal cells are found in the lining of a breast duct. A new study suggests that women who are diagnosed with abnormal cells in the lining of a breast duct—a noninvasive condition called ductal carcinoma in situ, or DCIS—generally have a low risk of dying from breast cancer.
Ductal carcinoma in situ DCISalso known as intraductal carcinomais a pre-cancerous or non-invasive cancerous lesion of the breast. In DCIS, abnormal cells are found in the lining of one or more milk ducts in the breast. In situ means "in place" and refers to the fact that the abnormal cells have not moved out of the mammary duct and into any of the surrounding tissues in the breast "pre-cancerous" refers to the fact that it has not yet become an invasive cancer.
DCIS is, if appropriately managed, a low-risk disease which has a small chance of impacting on patient life expectancy. However, despite significant advances in prognostic marker development in invasive breast cancer, there are no validated diagnostic assays to inform treatment choice for women with DCIS. Therefore we are unable to target effective treatment strategies to women at high risk and avoid over-treatment of women at low risk of progression to invasive breast cancer. Paradoxically, one effect of this uncertainty is undertreatment of some women.
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Ductal carcinoma in situ DCIS is non-invasive breast cancer. Ductal means that the cancer starts inside the milk ducts, carcinoma refers to any cancer that begins in the skin or other tissues including breast tissue that cover or line the internal organs, and in situ means "in its original place. When you have had DCIS, you are at higher risk for the cancer coming back or for developing a new breast cancer than a person who has never had breast cancer before.
Each breast contains 15 to 20 lobes of glandular tissue, arranged like the petals of a daisy. The lobes are further divided into smaller lobules that produce milk for breast-feeding. Small tubes ducts conduct the milk to a reservoir that lies just beneath your nipple.
In DCIS, the abnormal cells are contained in the milk ducts canals that carry milk from the lobules to the nipple openings during breastfeeding. DCIS is also called intraductal within the milk ducts carcinoma. Learn about treatment for early breast cancer. DCIS is non-invasive, but without treatment, the abnormal cells could progress to invasive cancer over time.
DCIS is diagnosed when the cells that line the milk ducts turn malignant, but are unable to penetrate through the wall of the duct noninvasiveso cannot get into the lymph nodes or blood stream. There is currently controversy about whether DCIS should be called breast cancer at all. DCIS has no accompanying symptoms.